¹College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Rampura Phul, Bathinda-151103, Punjab, INDIA DOI : 10.9775/kvfd.2025.35464 Arthropod-borne diseases pose a serious threat to livestock health and significantly impact the economic stability of the livestock sector. Among these, Lumpy Skin Disease (LSD), caused by the Lumpy Skin Disease Virus (LSDV) from the family Poxviridae, is a significant concern. Primarily affecting cattle, LSD is widespread in Asia and results in substantial economic losses. The disease is mainly transmitted by hematophagous vectors like stable flies -Stomoxys spp., Haematobia spp.[1], mosquitoes [2], and ticks- particularly those of the Hyalomma spp.[3] and Riphicephalus spp. [1,4]. Likewise, ticks serve as vectors for several hemoprotozoan pathogens such as Theileria spp., Babesia spp., and Anaplasma spp., which cause theileriosis, babesiosis, and anaplasmosis, respectively. In recent years, reports of co-infections involving LSD and hemoprotozoan parasites from endemic areas have increased. The overlapping ecology and shared tick vector populations facilitate the simultaneous transmission of LSDV and hemoprotozoa. These co-infections exacerbate clinical signs, delay recovery, and complicate diagnosis, leading to additional economic losses in affected herds. Keywords :