¹Department of Physical Education, Tarim University, Alar 843300, PR CHINA
²College of Animal Science and Technology, Tarim University, Alar 843300, PR CHINA DOI : 10.9775/kvfd.2023.30826 Regular exercise is known to confer various health benefits, but the specific impact of exercise intensity on antioxidant capacity and immune function remains complex and incompletely understood. Our study investigates the impact of exercise intensity on antioxidant capacity and immune function in mice. Mice were subjected to various exercise intensities (low, moderate, high) on a treadmill. Antioxidant enzyme activity, oxidative stress markers, ROS production, hemoglobin, hematocrit, leukocyte counts, lymphocyte subsets, and phagocytic activities were assessed. Exercise intensity influenced antioxidant enzyme activity, with low and high intensities showing significant effects. High-intensity exercise led to increased lipid peroxidation but improved the glutathione redox ratio. Exercise, irrespective of intensity, significantly affected immune function, notably increasing leukocyte counts, T-cell and B lymphocyte subsets, and phagocytic activities. Even at lower intensities, exercise profoundly impacts antioxidant capacity and immune function. These findings highlight the relationship between exercise, oxidative stress, and immune modulation. Keywords : Antioxidant activity, Immune response, Mice, Treadmill exercise